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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPIL4 All Species: 18.79
Human Site: T463 Identified Species: 29.52
UniProt: Q8WUA2 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WUA2 NP_624311.1 492 57225 T463 S H K S K Y Q T D L Y E R E R
Chimpanzee Pan troglodytes XP_527529 607 69328 T578 S H K S K Y Q T D L Y E R E R
Rhesus Macaque Macaca mulatta XP_001084421 492 57172 T463 S H K S K Y Q T D F Y E R E R
Dog Lupus familis XP_541147 492 57155 T463 S H K S K Y Q T D P Y E R E R
Cat Felis silvestris
Mouse Mus musculus Q9CXG3 492 57212 T463 S H K P K Y Q T E P Y E R E R
Rat Rattus norvegicus NP_001101927 357 40656 G329 V K W K G K G G K Y T K S D F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506397 487 56623 R459 S K S K D R C R E E P R E R E
Chicken Gallus gallus XP_419663 478 55881 E449 K H K D K Y R E D V R I R D W
Frog Xenopus laevis Q6GLX7 477 54856 A441 K S G K V K D A N M Q D E D T
Zebra Danio Brachydanio rerio NP_001121802 454 52864 D425 R D R E R Q K D K Q R E R G R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651291 653 75452 R498 E R R R S R S R D Q T G K R P
Honey Bee Apis mellifera XP_001121334 512 60307 D456 H K Q K K K H D N E K K R W N
Nematode Worm Caenorhab. elegans NP_492343 427 50388 N399 D R S Y R D N N R D R R D N H
Sea Urchin Strong. purpuratus XP_001192414 536 61906 Y503 R D T G R H G Y R D G D R D R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q871A4 494 56481 G460 L D R R D R R G D R S R D R Y
Conservation
Percent
Protein Identity: 100 80.8 98.7 98.1 N.A. 96.7 71.9 N.A. 77 80.8 23.5 69.7 N.A. 42.4 48.6 47.5 51.1
Protein Similarity: 100 80.8 98.9 98.7 N.A. 98.1 72.3 N.A. 86.1 89 45.7 81 N.A. 55.9 65.8 65.6 65.4
P-Site Identity: 100 100 93.3 93.3 N.A. 80 0 N.A. 6.6 40 0 20 N.A. 6.6 13.3 0 13.3
P-Site Similarity: 100 100 93.3 93.3 N.A. 86.6 13.3 N.A. 13.3 60 26.6 40 N.A. 20 33.3 6.6 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 43.5
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 60.7
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % C
% Asp: 7 20 0 7 14 7 7 14 47 14 0 14 14 27 0 % D
% Glu: 7 0 0 7 0 0 0 7 14 14 0 40 14 34 7 % E
% Phe: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 7 % F
% Gly: 0 0 7 7 7 0 14 14 0 0 7 7 0 7 0 % G
% His: 7 40 0 0 0 7 7 0 0 0 0 0 0 0 7 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % I
% Lys: 14 20 40 27 47 20 7 0 14 0 7 14 7 0 0 % K
% Leu: 7 0 0 0 0 0 0 0 0 14 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 7 7 14 0 0 0 0 7 7 % N
% Pro: 0 0 0 7 0 0 0 0 0 14 7 0 0 0 7 % P
% Gln: 0 0 7 0 0 7 34 0 0 14 7 0 0 0 0 % Q
% Arg: 14 14 20 14 20 20 14 14 14 7 20 20 60 20 47 % R
% Ser: 40 7 14 27 7 0 7 0 0 0 7 0 7 0 0 % S
% Thr: 0 0 7 0 0 0 0 34 0 0 14 0 0 0 7 % T
% Val: 7 0 0 0 7 0 0 0 0 7 0 0 0 0 0 % V
% Trp: 0 0 7 0 0 0 0 0 0 0 0 0 0 7 7 % W
% Tyr: 0 0 0 7 0 40 0 7 0 7 34 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _